Laptop curser not moving?

I have a Lenovo laptop with Windows Vista. The cursor is stuck in the middle of the screen and will not move. Please help. I tried press Ctrl alt delete to go to the control panel but the buttons won't work. The USB mouse won't work either. What do I do?

Try turning your laptop off and back on. That usually fixes the problem.

Even after turning off and back on the cursor is not moving on the laptop screen