What's wrong with my mouse drive/pointer drive?

I'm currently running a Lenovo desktop with windows 8.1. I've tried 3 different mice for my computer, and they all malfunction the same. How should I explain this? Well, every time I double click on a program on my desktop, it doesn't open, and it just instead acts as if I'm right clicking. But when I right click, it doesn't work. And it has nothing to do with the control panel, nothing is reversed, because everything is at default where the right click will give you the drop down menu, and the left click is for selecting. I mean, there will be times when it WILL work, if I restart my computer and let it sit for a few hours, but as I use it, more and more it fades back into not working again.
Oh and when I'm on the internet and with a tab open, I try to click in any text field, it doesn't work. It acts like I shifted to a different tab than what I was intended for.

Added (1). and it is NOT the mouse itself. Remember, I tried different mice, and I even have a Huion drawing tablet and it malfunctions the same as a mouse.

Call lenovo help at +1^800^256^7021.

Have you tried this… Go into control panel… Mouse… There you will see… Senesitvity settings… Try adjusting your mouse to how you click or double click on things…